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Cardinals Rally to Beat Seminoles 44-20

Jay Jacobs Published: October 10, 2026 | Updated: October 10, 2026 3 minutes read
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fsulouisville1

Louisville vs. FSU

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By: STEVE BITTENBENDER AP
LOUISVILLE, Ky. (AP) — Isaac Brown ran for a career-high 235 yards and two touchdowns on just 17 carries, including a game-changing 97-yard score, as Louisville rallied to take down Florida State 44-20 on Friday night.

W.#GoCards x @forthepeople pic.twitter.com/iJW4TSwV7o

— Louisville Football (@LouisvilleFB) October 10, 2026


Known for his big-play capabilities, Brown’s long touchdown run came on the first play of a second-quarter drive after Louisville DB Kaleb Beasley stopped Florida State WR Jasen Lopez at the Cardinals 3 on a fourth-and-goal. The Seminoles had led 14-0 and appeared to be in total control of the game.

Starting the weekend off right ‼️

Photo Gallery: https://t.co/uSS2ajF01A#GoCards pic.twitter.com/sPFjK2a6Wy

— Louisville Football (@LouisvilleFB) October 10, 2026


After the game, Florida State coach Mike Norvell said he still felt good about the play, a screen pass from Ashton Daniels to Lopez, with the possibility of going up by three touchdowns on the road.

Kaleb Beasley AGAIN 💥

Watch on @espn #GoCards pic.twitter.com/rhcG4OXiZ0

— Louisville Football (@LouisvilleFB) October 10, 2026


“Unfortunately, we didn’t do a good enough job in that moment,” said Norvell, whose team lost its 11th straight road game. “They’re pinned back. They got to go 98 yards, and they did it in one play.”

Isaac Brown. That's the tweet.

Watch on @espn #GoCards pic.twitter.com/k4t2MEB5nL

— Louisville Football (@LouisvilleFB) October 10, 2026


The touchdown run set a record for Louisville’s longest play from scrimmage, and Brown’s total for the night was the most for any running back among Football Bowl Subdivision programs this season.

Braxton Jennings to the 🏠

Watch on @espn #GoCards pic.twitter.com/Xo3OEz3GGy

— Louisville Football (@LouisvilleFB) October 10, 2026


Louisville (3-3, 2-2 Atlantic Coast Conference) outgained the Seminoles 438-190 after the fourth-down stop. The Cardinals finished with 537 yards. That included 397 overall on the ground, where they accounted for all of their touchdowns. It also happened despite Keyjuan Brown, the Cardinals’ top rusher this season, being sidelined with an injury.

ALL. THE. WAY 💨

Isaac Brown goes 97-yards to the house. The longest play in program history.

Watch on @espn #GoCards pic.twitter.com/UKU9qbJQfT

— Louisville Football (@LouisvilleFB) October 10, 2026


“Just when you think things are looking as bleak as they can, our guys hung in there,” said Louisville coach Jeff Brohm, whose team snapped a two-game skid. “You got to give our guys a ton of credit for playing hard, for finishing the game, for sticking together, for believing in themselves and their teammates. That’s not easy to do.’

Marquise Davis gets in 👊

Q2, 3:21 | Cards 14, Florida State 14#GoCards pic.twitter.com/PvAowKgQJY

— Louisville Football (@LouisvilleFB) October 10, 2026


Brown started the second half taking the opening kickoff 71 yards to the Seminoles 28 and got a horse-collar penalty added at the end. Four plays later, quarterback Lincoln Kienholz scored on a 3-yard run, his first of two scores, to give the Cardinals a 21-14 lead.

🗣️ WIN CAM#GoCards pic.twitter.com/lrbhLs23Fv

— Louisville Football (@LouisvilleFB) October 10, 2026


He then finished his night with a 68-yard touchdown run midway through the fourth quarter.

🎥: Head Coach Jeff Brohm press conference, Presented by @NeilHuffman 10-9-26 https://t.co/vTa5pJIvK6

— Louisville Football (@LouisvilleFB) October 10, 2026


Daniels completed 21 of 37 passes for 209 yards and two touchdowns as Florida State (3-3, 1-2) amassed 362 yards on offense. He also ran for a score.

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Jay Jacobs

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